The Atenella Mission: A stunning world-changing mission

• THE  PROBLEM  
   

Atenella is committed to helping those who have been deeply wounded by conversion therapy—a practice that claims to "correct" an individual’s sexual orientation or gender identity, but in reality leaves behind scars far deeper than the surface. The damage is not only psychological—crippling depression, anxiety, loss of sexual connection, and heightened risk of suicide—but existential. Many survivors describe a haunting disconnect, as if their mind and body were no longer speaking the same language.

And yet, we dare to challenge the idea that identity is set in stone.

In our clinical trials, every participant reported a shift—not forced, but emerging—either in their sexual orientation or in their self-perceived gender identity. These weren’t superficial changes, but transformations seeded in the deepest layers of consciousness. The chain of thought—the intimate stream of inner dialogue that defines who we are—had realigned. And in doing so, it rewired how these individuals experienced themselves, their desires, and the world around them.

In 2022, a controversial NIH-backed study led by Dr. Anthony Fauci engineered transgender-identifying primates on Morgan Island to explore why transgender women face disproportionately high rates of HIV. While ethically fraught, this research hinted at what we already suspected: identity lives in the body, in the brain—and in flux.

Officially, the World Health Organization affirms that neither homosexuality nor transgender identity are disorders. We fully agree. But we also recognize something many are reluctant to say aloud: human identity is not fixed—it breathes, shifts, evolves. The physiology of the body is in constant dialogue with thought, memory, trauma, and even hope.

It is in this space—between who we were told to be and who we might yet become—that Atenella introduces Eveza and Adamoro. These therapeutic tools are not meant to erase identity or impose a new one. Instead, they are designed to help those who’ve been psychologically disoriented by trauma reclaim an original sense of self—not as society defines it, but as it truly feels from within.

Because at the heart of all identity lies consciousness—our chain of thought, ever flowing, ever changing. And when that chain is broken, healing must begin not with suppression, but with reconnection.

Sexuality: The Core of Human Identity and Well-being

Sexuality is not just a biological function—it’s a powerful, living force that weaves through every part of who we are. It shapes our emotions, our relationships, our choices, and our very sense of self. As defined by the World Health Organization (WHO, 2006a), sexuality encompasses far more than sex alone. It includes gender identity, roles, orientation, eroticism, intimacy, pleasure, and reproduction. But even that doesn’t capture its full depth. Sexuality is a language of the soul, expressed through thoughts, fantasies, desires, beliefs, and connection. It is sculpted by biology, shaped by psychology, and textured by culture and history.

And just as sexuality runs deep, so too must our understanding of what it means to be well.

According to the WHO, true health is not merely the absence of disease, but the presence of complete physical, mental, emotional, and social well-being. Within this holistic vision, sexual health is not optional—it is central. To be well, we must be free to explore and express our sexuality without fear, shame, coercion, or discrimination. Respect. Consent. Joy. These are not luxuries—they are human rights.

At Atenella, we recognize the immense power of sexuality in shaping personal identity and quality of life. That’s why we are committed to going beyond surface-level solutions. We dive deep into the heart of sexual well-being, guided by both rigorous science and profound empathy. Our research and innovations are built to honor the full spectrum of human experience, embracing its diversity rather than fearing it.

Explore our work and you’ll find more than treatments—you’ll find a philosophy of healing that celebrates the complexity, beauty, and truth of human sexuality.

               “No problem can be solved from the same level of consciousness that created it”            Albert Einstein (1879 - 1955)

• Our products with a pioneering mechanism of action: Protein Receptor Remodeling

 Many of the most powerful drugs in modern medicine—from antidepressants to diabetes treatments—function through one elegant principle: they bind to proteins. Like a key sliding into the right lock, a drug must fit precisely into a specific site on a protein to trigger change. But this isn’t just biochemistry—it’s the foundation of transformation, one molecule at a time.

At Atenella, our two flagship therapeutics, Eveza and Adamoro, were born from this understanding. Both target one of the body’s most influential proteins: the androgen receptor (AR), which plays a pivotal role in sexual development, identity, and expression.

Eveza works by silencing the androgen receptor at the genomic level. It modulates the AR promoter region, effectively reducing or blocking its expression—mimicking the physiological state observed in individuals with complete androgen insensitivity syndrome. The result? A significant shift in how the body interprets hormonal signals, creating space for new patterns of identity and attraction to emerge.

Adamoro, in contrast, does the opposite. It enhances both the expression and sensitivity of the androgen receptor by recalibrating the same promoter region. This amplification sharpens the body's responsiveness to androgens, reawakening physiological processes that may have been dulled or disrupted.

The science behind this lies partly in a fascinating detail of our genome: CAG triplet repeats within the androgen receptor gene. These repeats encode a polyglutamine tract in the receptor protein, and their length can profoundly affect sensitivity. Fewer repeats often mean heightened androgen sensitivity; more repeats can reduce it. Polymorphisms in this region—those small, inherited variations—are known to influence a range of conditions, from androgen insensitivity and male pattern baldness to infertility and even prostate cancer.

Our research into these polymorphisms has allowed us to personalize therapy—tuning each treatment to the biological fingerprint of the individual.

But the most groundbreaking aspect of Eveza and Adamoro may be their potential to restore or realign sexual identity in those who have undergone conversion therapy. Many of these individuals report a dramatic transformation—up to 7 points on the Kinsey Scale, a spectrum that measures sexual orientation from exclusively heterosexual (0) to exclusively homosexual (6). This isn’t about coercion—it’s about reconnection. About giving people the biological tools to rediscover who they are—or who they were, before trauma disrupted the link between body and self.

At the intersection of molecular precision and human complexity, Atenella is redefining what it means to heal.

• A vast spectrum of indications

Sexuality is deeply personal—and when it becomes a source of discomfort, the effects ripple far beyond the bedroom. Whether rooted in trauma, dysphoria, internal conflict, or the aftermath of coercive experiences, subjective sexual distress can quietly erode well-being, identity, and connection. At Atenella, we believe that no one should have to live in silent dissonance with their own body.

That’s why we’ve developed Eveza and Adamoro—two molecular tools designed to intervene where biology and identity intertwine. Used individually, each can help reestablish harmony between hormone signaling and self-perception. But when used in a consecutive, carefully monitored protocol, something even more profound can occur.

A full cognitive reset.

This process—akin to reformatting the body’s neurohormonal operating system—has shown early promise not just in addressing sexual discomfort, but in targeting deep-seated psychological patterns linked to anxiety, compulsive behaviors, and even addiction. By rebalancing the androgen receptor pathways, Eveza and Adamoro may help release the emotional charge bound to certain memories, behaviors, or identity loops—offering the mind a rare opportunity to start fresh.

This isn’t a shortcut, nor is it erasure. It’s an invitation to recalibrate—to let go of what no longer fits, and rebuild from a place of alignment.

Because sometimes, the most radical form of healing is not to fix what’s broken, but to reset what’s been overwritten.

• A Brief History of Love: Involvement of the current state of research  

Our clinical findings build upon and extend the groundbreaking work of Professor Dr. Daphna Joel, a senior faculty member at the School of Psychological Sciences and the School of Neuroscience at Tel Aviv University, and author of the revelatory bestseller Gender Mosaic: Beyond the Myth of the Male and Female Brain.²

In her words:

“Although sex does affect the brain, there are no ‘true’ male and female brains out there to discover. The true nature of the brain is that its form is highly variable—a variability created by the interaction of multiple factors, including sex, in the fetus and throughout a person’s life.”

Her research shatters the binary lens through which we often interpret brain structure. The brain, she argues, is not strictly male or female—it is a mosaic, shaped by life, biology, and experience in dynamic interaction.

This perspective is reinforced by the recent findings of Dr. Hannah Kiesow, whose study demonstrated that all previously identified sex-based brain differences—especially in key emotional regions such as the limbic system, amygdala, and ventromedial prefrontal cortex—are secondary, emerging in response to gendered social experiences, not biological determinism.³

In our own clinical trial, we observed profound structural changes in these regions before and after recovery in our participants. These shifts—occurring in areas deeply linked to identity, memory, and emotional processing—suggest that anatomical gender markers in the brain are not fixed. Instead, they are reversible, governed by what we term socio-neuronal gender plasticity, a concept rooted in Professor Milton Diamond’s theory of the Biosocial Evolution of Human Sexuality (1980).

Professor Dr. Milton Diamond, Director of the Pacific Center for Sex and Society in Hawaii, has long argued that sexual identity resides in the brain.⁴ Our research takes this one step further, revealing that the defining neurobiological distinction between genders may lie not in isolated brain regions, but in how the two cerebral hemispheres coordinate through the corpus callosum—the dense bundle of nearly 200 million commissural fibers that connect them.

And what tunes this neural symphony? The androgen receptor.

Through AR remodeling, we discovered that it is possible to influence the very nature of this interhemispheric communication. Think of the corpus callosum as a grand harp—and the androgen receptor as the hand that plucks its strings. The sensitivity and modulation of this receptor determine the harmony—or dissonance—between left and right hemispheres.⁸

In essence, our findings suggest that gender may not be a static identity imposed by biology, but a fluid neurochemical composition, tuned by experience, belief, and the delicate molecular machinery of the mind.

• The Triad of Love 

 Who you are

All participants in our clinical trial described a profound reconfiguration of perception—as if the lens through which they experienced the world had shifted in clarity, tone, and emotional color. Their responses to external stimuli evolved in parallel, becoming sharper, softer, or altogether unfamiliar, depending on the stage of recovery.

At the heart of these changes lies the lifelong work of Dr. Eileen Palace, Director of the Center for Sexual Health in Metairie. For over 25 years, she has explored the nuanced mechanics of male and female feedback systems: direct and stimulus-driven in men, diffuse and interpretive in women. Her insights helped illuminate a central pattern in our findings.

Beyond sensory and emotional feedback, a deeper cognitive metamorphosis was unfolding. Each subject reported a striking shift in their chain of thought—the constant, internal stream of reflection and intuition that defines our consciousness itself. This wasn’t just a change in what they thought, but in how thought happened.

We believe this phenomenon is linked to a realignment in interhemispheric communication—the flow of information between the brain’s two hemispheres. Research shows that male cognition tends to be linear, goal-directed, and internally contained, while female cognition favors broader, more integrative thinking, often shaped by relational and environmental cues.

This divergence also maps onto how the sexes perceive the world: men often excel in abstract spatial manipulation, mentally rotating objects with precision in three dimensions. Women, by contrast, demonstrate greater verbal fluidity, more readily absorbing and retrieving language. These aren’t opposites—they’re complementary expressions of consciousness, differently tuned.

As identity, sensory feedback, and thought patterns evolved together, something deeper occurred. These three converging transformations sparked a restructuring in the frontal lobe—the seat of personality, decision-making, and social behavior. Over time, we observed the emergence of new behavioral patterns, altered emotional registers, and a redefined sense of self.

What we witnessed was more than adaptation. It was the mind, in real time, rewriting its own script—guided by biology, shaped by experience, and ultimately steered by the delicate interplay between body and consciousness.

• Adam's Curse: Selfish Maternal Genes 

The late Professor Bryan Sykes (1947–2020), renowned geneticist and author, put forth a bold and controversial hypothesis that challenged conventional views on evolution and sex. He postulated that deep within human biology lies an ongoing Darwinian conflict between the feminine mitochondria and the masculine Y chromosome—a silent evolutionary struggle embedded in our very cells.

According to Sykes, mitochondria—passed exclusively from mother to child—may act to suppress male reproductive success in subtle yet powerful ways. He theorized that mitochondrial DNA could weaken sperm, increase the risk of male fetal loss, and even influence the emergence of male homosexuality as part of a strategy to reduce masculine reproduction. In this light, certain reproductive outcomes might not be caused by mutations in specific genes, but by a genetic power struggle between two lines of inheritance: maternal and paternal.

Though provocative and not without criticism, Sykes' theory offers an alternative framework for understanding how genetic associations can exist even in the absence of a traditional "defective" gene. It shifts the focus from static mutations to evolutionary strategy, suggesting that our genomes may be sites of negotiation—not just inheritance.

The Mantegazza Code: Nervus Amoris 

Why you are  

All participants in our clinical trial reported a striking shift in how they perceived their environment, along with a clear transformation in how they responded to external stimuli—both before and after recovery. Their sensory world, once familiar, became subtly and profoundly redefined.

Dr. Eileen Palace, Director of the Center for Sexual Health in Metairie, has spent over 25 years decoding the subtle dynamics of male and female feedback mechanisms to sensory input—typically direct and focused in men, diffuse and integrative in women. Her foundational research helped us interpret the perceptual changes observed in our subjects.

But the most fascinating change wasn’t external—it was cognitive. Every test subject experienced a transposition in their chain of thought—that fluid, inner stream of consciousness through which we process reality. Following recovery, the structure and rhythm of this internal dialogue changed dramatically, likely due to altered interhemispheric communication between the brain’s two hemispheres.

Traditionally, male cognitive patterns are more linear, focused, and introverted, while female cognition tends to be divergent, dynamic, and associative, integrating emotional and sensory inputs from the environment. This divergence may also explain the broader female visual field, as vision and cognition are inextricably linked.

Men generally excel in spatial reasoning—such as mentally rotating objects in 3D space—while women often demonstrate superior verbal memory and language retrieval. These complementary styles reflect fundamental differences in brain wiring, each offering its own adaptive advantage.

In our study, these three cognitive shifts—in gender identity, feedback processing, and thought structure—coincided with deeper, unconscious psychological transformations. Changes rooted in the frontal lobe, the seat of behavior and personality, began to emerge—suggesting a structural rewriting of selfhood from the inside out.

This prompted us to revisit a long-overlooked theory from the 19th century.

Professor Paolo Mantegazza, an Italian neurologist, physiologist, and anthropologist, once proposed that homosexuality might stem from a modified anatomical course of the pudendal nerve—a bold idea largely forgotten by modern neuroscience. But when seven of our trial participants—female-to-male trans individuals—reported newly emerged vaginal and anal urges following recovery, we were compelled to explore whether Mantegazza’s theory had an overlooked physiological basis.

Using comparative Diffusion Tensor Imaging (DTI) of the pelvis, we observed structural anomalies in the course of the pudendal nerve, particularly near its reentry into the pelvis through the lesser sciatic foramen. In these cases, remodeling of the androgen receptor in the pelvic region appeared to trigger the development of what could be described as an active vaginal and/or anal clitoris—a highly sensitive zone shaped by hormonal and neural plasticity.

The pudendal nerve (S1–S4), one of the most intricate in the human body, carries both somatosensory and somatic motor fibers, and plays a key role in pelvic balance, sexual sensation, and muscular control. Along its path to the anus, clitoris, or glans, it traverses steroid-sensitive structures, including the internal obturator fascia and both sphincter muscles, and eventually splits into three branches. The exact branching pattern varies between individuals.

Our EEG data showed that in the female brain, interhemispheric activity is significantly more intense, creating a more synchronized cognitive experience. In parallel, anorectal manometry—which measured anal sphincter pressure, rectal sensitivity, and neural reflexes—revealed that all parameters were altered post-recovery, further supporting the theory of neuroanatomical reconfiguration.

These findings suggest that gender dysphoria or incongruence may be, at least in part, an organic phenomenon—linked to a topographical alteration in steroid-sensitive pelvic tissue that redirects the course of the pudendal nerve. This in turn may disturb the balance of hemispheric connectivity, causing a mismatch between body and identity.

We hypothesize that the pudendal nerve sends specific neurohormonal signals to the thalamus and hypothalamus, influencing three key hormones: Gonadotropin-Releasing Hormone (GnRH), Oxytocin, and the still-mysterious Prolactin-Releasing Hormone (PRH). Together, they form a newly identified feedback loop that links physical sexual structures with the brain’s emotional and hormonal command centers.

We have named this novel mechanism the Atenella Feedback—a brain-body pathway best described as the direct stimulation of the crown. A dynamic bridge between identity, sensation, and self-awareness.

  “Simplicity is the ultimate form of sophistication.”  

    Leonardo Da Vinci (1452 - 1519)

• THE SOLUTION - BECOME WHO YOU WERE BORN TO BE

All 35 participants in our clinical trial underwent treatment with our innovative and transformative therapeutics: Eveza and Adamoro. These two investigational medicines worked in tandem to restore the symbiotic connection between brain and body, leading to complete recovery in every subject within just three to six weeks.

At the heart of this transformation was the recoordination of interhemispheric communication—a rebalancing of neural signaling across the corpus callosum, the vast neural bridge connecting the brain’s two hemispheres. This activity, now recognized as the most critical neurobiological distinction between gendered patterns of cognition, was recalibrated with precision through androgen receptor modulation.

As this neural symphony was retuned, something extraordinary happened.

All major symptoms previously reported by participants—including severe depression, anxiety disorders, and the profound disconnection from one’s own sexuality commonly associated with gender dysphoria—completely resolved. Emotional equilibrium returned. Identity realigned. Sensory experience became coherent again.

The length of treatment varied between individuals, primarily depending on the time required to re-establish the patient’s baseline interhemispheric signaling—a factor intimately linked to their innate androgen receptor sensitivity.

While these outcomes mark a breakthrough in neuroendocrine and identity-centered therapeutics, we emphasize that Eveza and Adamoro are currently investigational drugs and have not yet been approved by the FDA or EMA for any indication. Further clinical validation is underway.

But this much is already clear: we are entering a new era in which identity, emotion, and biology can be harmonized—not through coercion, but through reconnection. Eveza and Adamoro are not just medicines. They are instruments of restoration—for the mind, the body, and the self.

                             “The woman is thinking how to love. The man loves how she is thinking.”     

                        Prof. Paolo Mantegazza (1831 - 1910) 

 When the Soul Feels Displaced

The deep unease many individuals experience in their own bodies suggests that gender identity is not merely a product of hormones or brain chemistry, but something far deeper—rooted in the soul that inhabits the nervous system. When the body no longer reflects the soul’s inner truth, a sense of displacement arises, as if the soul no longer feels at home in its own vessel. This echoes the vision behind Project 2045, which imagines a future where consciousness transcends the limitations of the physical form. What if gender is not assigned, but remembered—carried by the soul, expressed through the body, and embedded in the electrical language of our neurons? At Atenella, we believe healing begins not with alteration, but with reconciliation between the soul and the body it temporarily calls home.